Hyperplasia and hypertrophia in the denervated and distended rat urinary bladder

J Ekström, Anne-Charlotte Henningsson, S Henningsson, Lars Malmberg

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskriftPeer review

Sammanfattning

The parasympathetically denervated and distended rat urinary bladder was found to have increased fourfold in weight when examined 3 weeks postoperatively. Both in muscularis and mucosa of such a bladder the synthesis of proteins, RNA and DNA was increased severalfold. An increase in the polyamines putrescine, spermidine and spermine was also found; these polyamines are usually linked to protein synthesis. The results suggest that the cells of the two layers increase both in size and number. Hyperplasia was, in a previous study, suggested as a possible explanation for a right-ward shift of the active length-tension curve of muscle strips in the denervated rat urinary bladder.
Originalspråkengelska
Sidor (från-till)45-48
TidskriftActa Physiologica Scandinavica
Volym122
Nummer1
StatusPublished - 1984

Bibliografisk information

The information about affiliations in this record was updated in December 2015.
The record was previously connected to the following departments: Department of Urology, Lund (013077000), Pediatrics/Urology/Gynecology/Endocrinology (013240400)

Ämnesklassifikation (UKÄ)

  • Urologi och njurmedicin
  • Klinisk medicin

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