Immune functions of platelets

Rick Kapur, John W. Semple

Forskningsoutput: Kapitel i bok/rapport/Conference proceedingKapitel samlingsverkForskningPeer review

Sammanfattning

Platelets are megakaryocyte-derived cellular fragments lacking a nucleus and are classically known for their crucial role in supporting hemostasis. Besides their hemostatic function, it is becoming increasingly clear that platelets are much more diverse and that they are capable of a wide range of immune-sensing functions. This chapter will focus on these non-hemostatic immunological aspects, especially in an inflammatory setting. The cross talk between platelets and pathogens as well as between platelets and various target cells will be discussed, in order to highlight the emerging and important immune features of platelets.
Originalspråkengelska
Titel på värdpublikationAntibody Therapy
Undertitel på värdpublikationSubstitution - Immunomodulation - Monoclonal Immunotherapy
RedaktörerPaul Imbach
FörlagSpringer
Kapitel17
Sidor241-259
Antal sidor19
ISBN (elektroniskt)9783319680385
ISBN (tryckt)9783319680378
DOI
StatusPublished - 2018 mars 30

Ämnesklassifikation (UKÄ)

  • Immunologi inom det medicinska området
  • Immunologi

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