Sammanfattning
Platelets are megakaryocyte-derived cellular fragments lacking a nucleus and are classically known for their crucial role in supporting hemostasis. Besides their hemostatic function, it is becoming increasingly clear that platelets are much more diverse and that they are capable of a wide range of immune-sensing functions. This chapter will focus on these non-hemostatic immunological aspects, especially in an inflammatory setting. The cross talk between platelets and pathogens as well as between platelets and various target cells will be discussed, in order to highlight the emerging and important immune features of platelets.
Originalspråk | engelska |
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Titel på värdpublikation | Antibody Therapy |
Undertitel på värdpublikation | Substitution - Immunomodulation - Monoclonal Immunotherapy |
Redaktörer | Paul Imbach |
Förlag | Springer |
Kapitel | 17 |
Sidor | 241-259 |
Antal sidor | 19 |
ISBN (elektroniskt) | 9783319680385 |
ISBN (tryckt) | 9783319680378 |
DOI | |
Status | Published - 2018 mars 30 |
Ämnesklassifikation (UKÄ)
- Immunologi inom det medicinska området
- Immunologi