iNOS affects matrix production in distal lung fibroblasts from patients with mild asthma.

Anna-Karin Larsson Callerfelt; Maria Weitoft; Kristian Nihlberg; Leif Bjermer; Gunilla Westergren-Thorsson; Ellen Tufvesson

doi:10.1016/j.pupt.2015.09.003

iNOS affects matrix production in distal lung fibroblasts from patients with mild asthma.

Anna-Karin Larsson Callerfelt, Maria Weitoft, Kristian Nihlberg, Leif Bjermer, Gunilla Westergren-Thorsson, Ellen Tufvesson

Forskningsoutput: Tidskriftsbidrag › Översiktsartikel › Peer review

265 Nedladdningar (Pure)

Sammanfattning

A high level of exhaled nitric oxide (NO) is a marker for inflammation in the airways of asthmatic subjects. However, little is known about how NO and inducible nitric oxides synthase (iNOS) activity may affect remodelling in the distal lung. We hypothesized that there is a link between iNOS and ongoing remodelling processes in the distal lung of mild asthmatics.

Originalspråk	engelska
Sidor (från-till)	64-71
Tidskrift	Pulmonary Pharmacology & Therapeutics
Volym	34
Nummer	sep 9
DOI	https://doi.org/10.1016/j.pupt.2015.09.003
Status	Published - 2015

Ämnesklassifikation (UKÄ)

Lungmedicin och allergi

Tillgång till dokument

10.1016/j.pupt.2015.09.003

Elsevier Larsson Callerfelt et alAccepterat manuskript från författare, 475 KB

http://www.ncbi.nlm.nih.gov/pubmed/26362859?dopt=Abstract

1 Doktorsavhandling (sammanläggning)

Extracellular Matrix Alterations in Patients with Different Phenotypes of Asthma.
Weitoft, M., 2017, Lund: Lund University: Faculty of Medicine. 76 s.
Forskningsoutput: Avhandling › Doktorsavhandling (sammanläggning)

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@article{0d20c763ca0e45baabfd2a5204502aba,

title = "iNOS affects matrix production in distal lung fibroblasts from patients with mild asthma.",

abstract = "A high level of exhaled nitric oxide (NO) is a marker for inflammation in the airways of asthmatic subjects. However, little is known about how NO and inducible nitric oxides synthase (iNOS) activity may affect remodelling in the distal lung. We hypothesized that there is a link between iNOS and ongoing remodelling processes in the distal lung of mild asthmatics.",

author = "{Larsson Callerfelt}, Anna-Karin and Maria Weitoft and Kristian Nihlberg and Leif Bjermer and Gunilla Westergren-Thorsson and Ellen Tufvesson",

year = "2015",

doi = "10.1016/j.pupt.2015.09.003",

language = "English",

volume = "34",

pages = "64--71",

journal = "Pulmonary Pharmacology & Therapeutics",

issn = "1522-9629",

publisher = "Elsevier",

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TY - JOUR

T1 - iNOS affects matrix production in distal lung fibroblasts from patients with mild asthma.

AU - Larsson Callerfelt, Anna-Karin

AU - Weitoft, Maria

AU - Nihlberg, Kristian

AU - Bjermer, Leif

AU - Westergren-Thorsson, Gunilla

AU - Tufvesson, Ellen

PY - 2015

Y1 - 2015

N2 - A high level of exhaled nitric oxide (NO) is a marker for inflammation in the airways of asthmatic subjects. However, little is known about how NO and inducible nitric oxides synthase (iNOS) activity may affect remodelling in the distal lung. We hypothesized that there is a link between iNOS and ongoing remodelling processes in the distal lung of mild asthmatics.

AB - A high level of exhaled nitric oxide (NO) is a marker for inflammation in the airways of asthmatic subjects. However, little is known about how NO and inducible nitric oxides synthase (iNOS) activity may affect remodelling in the distal lung. We hypothesized that there is a link between iNOS and ongoing remodelling processes in the distal lung of mild asthmatics.

U2 - 10.1016/j.pupt.2015.09.003

DO - 10.1016/j.pupt.2015.09.003

M3 - Review article

C2 - 26362859

SN - 1522-9629

VL - 34

SP - 64

EP - 71

JO - Pulmonary Pharmacology & Therapeutics

JF - Pulmonary Pharmacology & Therapeutics

IS - sep 9

ER -

iNOS affects matrix production in distal lung fibroblasts from patients with mild asthma.

Sammanfattning

Ämnesklassifikation (UKÄ)

Tillgång till dokument

Fingeravtryck

Forskningsoutput

Extracellular Matrix Alterations in Patients with Different Phenotypes of Asthma.

Citera det här