Instantaneous Wave-Free Ratio versus Fractional Flow Reserve guided intervention (iFR-SWEDEHEART): Rationale and design of a multicenter, prospective, registry-based randomized clinical trial.

Matthias Götberg, Evald H Christiansen, Ingibjörg Gudmundsdottir, Lennart Sandhall, Elmir Omerovic, Stefan K James, David Erlinge, Ole Fröbert

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskriftPeer review

22 !!Citations (SciVal)

Sammanfattning

Instantaneous wave-free ratio (iFR) is a new hemodynamic resting index for assessment of coronary artery stenosis severity. iFR uses high frequency sampling to calculate a gradient across a coronary lesion during a period of diastole. The index has been tested against fractional flow reserve (FFR) and found to have an overall classification agreement of 80% to 85%. Whether the level of disagreement is clinically relevant is unknown. Clinical outcome data on iFR are scarce. This study is a registry-based randomized clinical trial, which is a novel strategy using health quality registries as on-line platforms for randomization, case record forms, and follow-up.
Originalspråkengelska
Sidor (från-till)945-950
TidskriftAmerican Heart Journal
Volym170
Utgåva5
DOI
StatusPublished - 2015

Ämnesklassifikation (UKÄ)

  • Kardiologi

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