Intranasal Immunization of Mice with Group B Streptococcal Protein Rib and Cholera Toxin B Subunit Confers Protection against Lethal Infection.

Charlotte U Larsson, Jan Holmgren, Gunnar Lindahl, Charlotta Bergquist

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskriftPeer review

22 Citeringar (SciVal)
150 Nedladdningar (Pure)

Sammanfattning

Intranasal immunization of mice with Rib, a cell surface protein of group B streptococcus (GBS), conjugated to or simply coadministered with the recombinant cholera toxin B subunit, induces systemic immunoglobulin G (IgG) and local IgA antibody responses and confers protection against lethal GBS infection. These findings have implications for the development of a human GBS vaccine.
Originalspråkengelska
Sidor (från-till)1184-1187
TidskriftInfection and Immunity
Volym72
Utgåva2
DOI
StatusPublished - 2004

Ämnesklassifikation (UKÄ)

  • Mikrobiologi inom det medicinska området

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