Ischaemic brain damage after cardiac arrest and induced hypothermia-a systematic description of selective eosinophilic neuronal death. A neuropathologic study of 23 patients.

Erik Björklund; Eva Lindberg; Malin Rundgren; Tobias Cronberg; Hans Friberg; Elisabet Englund

doi:10.1016/j.resuscitation.2013.11.022

Ischaemic brain damage after cardiac arrest and induced hypothermia-a systematic description of selective eosinophilic neuronal death. A neuropathologic study of 23 patients.

Erik Björklund, Eva Lindberg, Malin Rundgren, Tobias Cronberg, Hans Friberg, Elisabet Englund

Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

Sammanfattning

Although well characterized in animals, brain damage in humans treated with hypothermia after cardiac arrest has not been systematically explored. In this study we aimed to describe the characteristic trait of selective eosinophilic neuronal death (SEND), and its correlation with time to return of spontaneous circulation (ROSC) in cardiac arrest patients who died after hypothermia treatment and were referred for autopsy.

Originalspråk	engelska
Sidor (från-till)	527-532
Tidskrift	Resuscitation
Volym	85
Nummer	4
DOI	https://doi.org/10.1016/j.resuscitation.2013.11.022
Status	Published - 2014

Bibliografisk information

The information about affiliations in this record was updated in December 2015.
The record was previously connected to the following departments: Anaesthesiology and Intensive Care (013230022), Neurology, Lund (013027000), Pathology, (Lund) (013030000)

Ämnesklassifikation (UKÄ)

Anestesi och intensivvård

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10.1016/j.resuscitation.2013.11.022

http://www.ncbi.nlm.nih.gov/pubmed/24321320?dopt=Abstract

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title = "Ischaemic brain damage after cardiac arrest and induced hypothermia-a systematic description of selective eosinophilic neuronal death. A neuropathologic study of 23 patients.",

abstract = "Although well characterized in animals, brain damage in humans treated with hypothermia after cardiac arrest has not been systematically explored. In this study we aimed to describe the characteristic trait of selective eosinophilic neuronal death (SEND), and its correlation with time to return of spontaneous circulation (ROSC) in cardiac arrest patients who died after hypothermia treatment and were referred for autopsy.",

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note = "The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Anaesthesiology and Intensive Care (013230022), Neurology, Lund (013027000), Pathology, (Lund) (013030000)",

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doi = "10.1016/j.resuscitation.2013.11.022",

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Ischaemic brain damage after cardiac arrest and induced hypothermia-a systematic description of selective eosinophilic neuronal death. A neuropathologic study of 23 patients. / Björklund, Erik; Lindberg, Eva; Rundgren, Malin et al.
I: Resuscitation, Vol. 85, Nr. 4, 2014, s. 527-532.

Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

TY - JOUR

T1 - Ischaemic brain damage after cardiac arrest and induced hypothermia-a systematic description of selective eosinophilic neuronal death. A neuropathologic study of 23 patients.

AU - Björklund, Erik

AU - Lindberg, Eva

AU - Rundgren, Malin

AU - Cronberg, Tobias

AU - Friberg, Hans

AU - Englund, Elisabet

N1 - The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Anaesthesiology and Intensive Care (013230022), Neurology, Lund (013027000), Pathology, (Lund) (013030000)

PY - 2014

Y1 - 2014

N2 - Although well characterized in animals, brain damage in humans treated with hypothermia after cardiac arrest has not been systematically explored. In this study we aimed to describe the characteristic trait of selective eosinophilic neuronal death (SEND), and its correlation with time to return of spontaneous circulation (ROSC) in cardiac arrest patients who died after hypothermia treatment and were referred for autopsy.

AB - Although well characterized in animals, brain damage in humans treated with hypothermia after cardiac arrest has not been systematically explored. In this study we aimed to describe the characteristic trait of selective eosinophilic neuronal death (SEND), and its correlation with time to return of spontaneous circulation (ROSC) in cardiac arrest patients who died after hypothermia treatment and were referred for autopsy.

U2 - 10.1016/j.resuscitation.2013.11.022

DO - 10.1016/j.resuscitation.2013.11.022

M3 - Article

C2 - 24321320

SN - 1873-1570

VL - 85

SP - 527

EP - 532

JO - Resuscitation

JF - Resuscitation

IS - 4

ER -

Ischaemic brain damage after cardiac arrest and induced hypothermia-a systematic description of selective eosinophilic neuronal death. A neuropathologic study of 23 patients.

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Bibliografisk information

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