Label-free and non-contact platelet analysis platform

E Persson; Carl Johannesson; David Erlinge; Mikael Evander

Label-free and non-contact platelet analysis platform

E Persson, Carl Johannesson, David Erlinge, Mikael Evander

Forskningsoutput: Kapitel i bok/rapport/Conference proceeding › Konferenspaper i proceeding › Peer review

Sammanfattning

We present a non-contact platelet functional analysis platform based on acoustic trapping of platelet clusters and activation monitoring using impedance spectroscopy. The system was characterized using polystyrene particles and human platelets. The system was also capable of transferring platelets from plasma into a controlled buffer. Trapped platelets were activated using 20 and 40 μM TRAP and their responses were recorded with impedance spectroscopy. The system shows great promise as a miniaturized, automatable platform for platelet analysis.

Originalspråk	engelska
Titel på värdpublikation	18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
Förlag	Chemical and Biological Microsystems Society
Sidor	2542-2543
Antal sidor	2
ISBN (tryckt)	9780979806476
Status	Published - 2014
Evenemang	18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, USA Varaktighet: 2014 okt. 26 → 2014 okt. 30 Konferensnummer: 18

Konferens

Konferens	18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
Land/Territorium	USA
Ort	San Antonio
Period	2014/10/26 → 2014/10/30

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@inproceedings{03c0ef74464e4398a6298b2557f4f0ac,

title = "Label-free and non-contact platelet analysis platform",

abstract = "We present a non-contact platelet functional analysis platform based on acoustic trapping of platelet clusters and activation monitoring using impedance spectroscopy. The system was characterized using polystyrene particles and human platelets. The system was also capable of transferring platelets from plasma into a controlled buffer. Trapped platelets were activated using 20 and 40 μM TRAP and their responses were recorded with impedance spectroscopy. The system shows great promise as a miniaturized, automatable platform for platelet analysis.",

keywords = "Acoustic trapping, Impedance spectroscopy, Platelet functional analysis",

author = "E Persson and Carl Johannesson and David Erlinge and Mikael Evander",

year = "2014",

language = "English",

isbn = "9780979806476",

pages = "2542--2543",

booktitle = "18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014",

publisher = "Chemical and Biological Microsystems Society",

note = "18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 ; Conference date: 26-10-2014 Through 30-10-2014",

}

Persson, E, Johannesson, C, Erlinge, D & Evander, M 2014, Label-free and non-contact platelet analysis platform. i 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. Chemical and Biological Microsystems Society, s. 2542-2543, 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014, San Antonio, USA, 2014/10/26.

Label-free and non-contact platelet analysis platform. / Persson, E; Johannesson, Carl; Erlinge, David et al.
18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014. Chemical and Biological Microsystems Society, 2014. s. 2542-2543.

Forskningsoutput: Kapitel i bok/rapport/Conference proceeding › Konferenspaper i proceeding › Peer review

TY - GEN

T1 - Label-free and non-contact platelet analysis platform

AU - Persson, E

AU - Johannesson, Carl

AU - Erlinge, David

AU - Evander, Mikael

N1 - Conference code: 18

PY - 2014

Y1 - 2014

N2 - We present a non-contact platelet functional analysis platform based on acoustic trapping of platelet clusters and activation monitoring using impedance spectroscopy. The system was characterized using polystyrene particles and human platelets. The system was also capable of transferring platelets from plasma into a controlled buffer. Trapped platelets were activated using 20 and 40 μM TRAP and their responses were recorded with impedance spectroscopy. The system shows great promise as a miniaturized, automatable platform for platelet analysis.

AB - We present a non-contact platelet functional analysis platform based on acoustic trapping of platelet clusters and activation monitoring using impedance spectroscopy. The system was characterized using polystyrene particles and human platelets. The system was also capable of transferring platelets from plasma into a controlled buffer. Trapped platelets were activated using 20 and 40 μM TRAP and their responses were recorded with impedance spectroscopy. The system shows great promise as a miniaturized, automatable platform for platelet analysis.

KW - Acoustic trapping

KW - Impedance spectroscopy

KW - Platelet functional analysis

M3 - Paper in conference proceeding

AN - SCOPUS:84941643558

SN - 9780979806476

SP - 2542

EP - 2543

BT - 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014

PB - Chemical and Biological Microsystems Society

T2 - 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014

Y2 - 26 October 2014 through 30 October 2014

ER -

Label-free and non-contact platelet analysis platform

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