@inproceedings{7d60b8868dcc4b04a6c0f31339fee203,
title = "Left and Right Atrial Contribution to the P-wave in Realistic Computational Models",
abstract = "ECG markers derived from the P-wave are used frequently to assess atrial function and anatomy, e.g. left atrial enlargement. While having the advantage of being routinely acquired, the processes underlying the genesis of the P-wave are not understood in their entirety. Particularly the distinct contributions of the two atria have not been analyzed mechanistically. We used an in silico approach to simulate P-waves originating from the left atrium (LA) and the right atrium (RA) separately in two realistic models. LA contribution to the P-wave integral was limited to 30% or less. Around 20% could be attributed to the first third of the P-wave which reflected almost only RA depolarization. Both atria contributed to the second and last third with RA contribution being about twice as large as LA contribution. Our results foster the comprehension of the difficulties related to ECG-based LA assessment.",
keywords = "atrial enlargement, Left, Mathematical modeling, P-wave, Electrocardiogram, Atrial modeling",
author = "Axel Loewe and Krueger, {Martin W.} and Pyotr Platonov and Fredrik Holmqvist and Olaf Doessel and Gunnar Seemann",
year = "2015",
doi = "10.1007/978-3-319-20309-6_50",
language = "English",
volume = "9126",
publisher = "Springer",
pages = "439--447",
booktitle = "Lecture Notes in Computer Science",
address = "Germany",
note = "8th International Conference on Functional Imaging and Modeling of the Heart(FIMH) ; Conference date: 25-06-2015 Through 27-06-2015",
}