Limited effects of temafloxacin compared with ciprofloxacin on T- lymphocyte function

Kristian Riesbeck; Arne Forsgren

doi:10.1128/AAC.38.4.879

Limited effects of temafloxacin compared with ciprofloxacin on T- lymphocyte function

Kristian Riesbeck, Arne Forsgren

Klinisk mikrobiologi, Malmö

Skåne University Hospital

Forskningsoutput: Tidskriftsbidrag › Debate/Note/Editorial › Peer review

Sammanfattning

Temafloxacin increased interleukin-2 production and mRNA levels and enhanced thymidine incorporation in stimulated lymphocyte cultures. Gamma interferon mRNA levels were unaffected. Temafloxacin also stimulated interleukin-2 gene induction, as revealed in a chloramphenicol acetyltransferase reporter gene system. However, temafloxacin exerted significantly weaker effects in these respects than did ciprofloxacin.

Originalspråk	engelska
Sidor (från-till)	879-882
Tidskrift	Antimicrobial Agents and Chemotherapy
Volym	38
Nummer	4
DOI	https://doi.org/10.1128/AAC.38.4.879
Status	Published - 1994 jan. 1

Ämnesklassifikation (UKÄ)

Cancer och onkologi

FN:s Globala mål

Denna forskningsoutput relaterar till följande Globala mål

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10.1128/AAC.38.4.879

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title = "Limited effects of temafloxacin compared with ciprofloxacin on T- lymphocyte function",

abstract = "Temafloxacin increased interleukin-2 production and mRNA levels and enhanced thymidine incorporation in stimulated lymphocyte cultures. Gamma interferon mRNA levels were unaffected. Temafloxacin also stimulated interleukin-2 gene induction, as revealed in a chloramphenicol acetyltransferase reporter gene system. However, temafloxacin exerted significantly weaker effects in these respects than did ciprofloxacin.",

author = "Kristian Riesbeck and Arne Forsgren",

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N2 - Temafloxacin increased interleukin-2 production and mRNA levels and enhanced thymidine incorporation in stimulated lymphocyte cultures. Gamma interferon mRNA levels were unaffected. Temafloxacin also stimulated interleukin-2 gene induction, as revealed in a chloramphenicol acetyltransferase reporter gene system. However, temafloxacin exerted significantly weaker effects in these respects than did ciprofloxacin.

AB - Temafloxacin increased interleukin-2 production and mRNA levels and enhanced thymidine incorporation in stimulated lymphocyte cultures. Gamma interferon mRNA levels were unaffected. Temafloxacin also stimulated interleukin-2 gene induction, as revealed in a chloramphenicol acetyltransferase reporter gene system. However, temafloxacin exerted significantly weaker effects in these respects than did ciprofloxacin.

U2 - 10.1128/AAC.38.4.879

DO - 10.1128/AAC.38.4.879

M3 - Debate/Note/Editorial

C2 - 8031064

AN - SCOPUS:0028265747

SN - 0066-4804

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SP - 879

EP - 882

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

IS - 4

ER -

Limited effects of temafloxacin compared with ciprofloxacin on T- lymphocyte function

Sammanfattning

Ämnesklassifikation (UKÄ)

FN:s Globala mål

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