Measuring early vascular aging in youth: An expert consensus document from the Youth Vascular Consortium

Jeanne Hersant; Ruan Kruger; Elisabetta Bianchini; Karsten Königstein; Manish D Sinha; Erzsébet V Hidvégi; Vimarsha Kodithuwakku; José Geraldo Mill; Alejandro Diaz; Yanina Zócalo; Daniel Bia; David Celermajer; Henner Hanssen; Madeleine Johansson; Giacomo Pucci; Mieczysław Litwin; Keeron Stone; Christopher J A Pugh; Lee Stoner; Elaine M Urbina; Rosa Maria Bruno; Peter M Nilsson; Rachel E Climie

doi:10.1097/HJH.0000000000004039

Measuring early vascular aging in youth: An expert consensus document from the Youth Vascular Consortium

Jeanne Hersant, Ruan Kruger, Elisabetta Bianchini, Karsten Königstein, Manish D Sinha, Erzsébet V Hidvégi, Vimarsha Kodithuwakku, José Geraldo Mill, Alejandro Diaz, Yanina Zócalo, Daniel Bia, David Celermajer, Henner Hanssen, Madeleine Johansson, Giacomo Pucci, Mieczysław Litwin, Keeron Stone, Christopher J A Pugh, Lee Stoner, Elaine M UrbinaRosa Maria Bruno, Peter M Nilsson, Rachel E Climie

Forskningsoutput: Tidskriftsbidrag › Översiktsartikel › Peer review

Sammanfattning

Since the conceptualization of early vascular aging (EVA) in 2008, significant efforts have been made to develop and improve its assessment. Initially lead by the investigation of arterial stiffness through pulse wave velocity (PWV), several additional vascular aging biomarkers have gained prominence in recent years. Despite expanding literature addressing methodological concerns associated with these biomarkers in youth, a standardized approach for clinical evaluation of EVA remains elusive, leaving pertinent gaps in understanding the optimal methodology. This article, resulting from international consensus efforts from the Youth Vascular Consortium, aims to provide an updated overview of methods available to measure EVA in youth and to discuss challenges in translating these methods into clinical practice.

Originalspråk	engelska
Tidskrift	Journal of Hypertension
DOI	https://doi.org/10.1097/HJH.0000000000004039
Status	E-pub ahead of print - 2025 maj 6

Bibliografisk information

Ämnesklassifikation (UKÄ)

Kardiologi och kardiovaskulära sjukdomar

FN:s Globala mål

Denna forskningsoutput relaterar till följande Globala mål

Tillgång till dokument

10.1097/HJH.0000000000004039

Vascular Ageing and Arterial Stiffness in the Swedish Population
Johansson, M. (Forskare), Nilsson, P. M. (Forskare) & Engström, G. (Forskare)
Hjärt-Lungfonden
2021/10/21 → …
Projekt: Forskning

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Hersant, J., Kruger, R., Bianchini, E., Königstein, K., Sinha, M. D., Hidvégi, E. V., Kodithuwakku, V., Mill, J. G., Diaz, A., Zócalo, Y., Bia, D., Celermajer, D., Hanssen, H., Johansson, M., Pucci, G., Litwin, M., Stone, K., Pugh, C. J. A., Stoner, L., ... Climie, R. E. (2025). Measuring early vascular aging in youth: An expert consensus document from the Youth Vascular Consortium. Journal of Hypertension. Avancerad onlinepublikation. https://doi.org/10.1097/HJH.0000000000004039

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title = "Measuring early vascular aging in youth: An expert consensus document from the Youth Vascular Consortium",

abstract = "Since the conceptualization of early vascular aging (EVA) in 2008, significant efforts have been made to develop and improve its assessment. Initially lead by the investigation of arterial stiffness through pulse wave velocity (PWV), several additional vascular aging biomarkers have gained prominence in recent years. Despite expanding literature addressing methodological concerns associated with these biomarkers in youth, a standardized approach for clinical evaluation of EVA remains elusive, leaving pertinent gaps in understanding the optimal methodology. This article, resulting from international consensus efforts from the Youth Vascular Consortium, aims to provide an updated overview of methods available to measure EVA in youth and to discuss challenges in translating these methods into clinical practice.",

author = "Jeanne Hersant and Ruan Kruger and Elisabetta Bianchini and Karsten K{\"o}nigstein and Sinha, {Manish D} and Hidv{\'e}gi, {Erzs{\'e}bet V} and Vimarsha Kodithuwakku and Mill, {Jos{\'e} Geraldo} and Alejandro Diaz and Yanina Z{\'o}calo and Daniel Bia and David Celermajer and Henner Hanssen and Madeleine Johansson and Giacomo Pucci and Mieczys{\l}aw Litwin and Keeron Stone and Pugh, {Christopher J A} and Lee Stoner and Urbina, {Elaine M} and Bruno, {Rosa Maria} and Nilsson, {Peter M} and Climie, {Rachel E}",

year = "2025",

month = may,

day = "6",

doi = "10.1097/HJH.0000000000004039",

language = "English",

journal = "Journal of Hypertension",

issn = "1473-5598",

publisher = "Lippincott Williams & Wilkins",

}

Hersant, J, Kruger, R, Bianchini, E, Königstein, K, Sinha, MD, Hidvégi, EV, Kodithuwakku, V, Mill, JG, Diaz, A, Zócalo, Y, Bia, D, Celermajer, D, Hanssen, H, Johansson, M, Pucci, G, Litwin, M, Stone, K, Pugh, CJA, Stoner, L, Urbina, EM, Bruno, RM, Nilsson, PM & Climie, RE 2025, 'Measuring early vascular aging in youth: An expert consensus document from the Youth Vascular Consortium', Journal of Hypertension. https://doi.org/10.1097/HJH.0000000000004039

TY - JOUR

T1 - Measuring early vascular aging in youth

T2 - An expert consensus document from the Youth Vascular Consortium

AU - Hersant, Jeanne

AU - Kruger, Ruan

AU - Bianchini, Elisabetta

AU - Königstein, Karsten

AU - Sinha, Manish D

AU - Hidvégi, Erzsébet V

AU - Kodithuwakku, Vimarsha

AU - Mill, José Geraldo

AU - Diaz, Alejandro

AU - Zócalo, Yanina

AU - Bia, Daniel

AU - Celermajer, David

AU - Hanssen, Henner

AU - Johansson, Madeleine

AU - Pucci, Giacomo

AU - Litwin, Mieczysław

AU - Stone, Keeron

AU - Pugh, Christopher J A

AU - Stoner, Lee

AU - Urbina, Elaine M

AU - Bruno, Rosa Maria

AU - Nilsson, Peter M

AU - Climie, Rachel E

PY - 2025/5/6

Y1 - 2025/5/6

N2 - Since the conceptualization of early vascular aging (EVA) in 2008, significant efforts have been made to develop and improve its assessment. Initially lead by the investigation of arterial stiffness through pulse wave velocity (PWV), several additional vascular aging biomarkers have gained prominence in recent years. Despite expanding literature addressing methodological concerns associated with these biomarkers in youth, a standardized approach for clinical evaluation of EVA remains elusive, leaving pertinent gaps in understanding the optimal methodology. This article, resulting from international consensus efforts from the Youth Vascular Consortium, aims to provide an updated overview of methods available to measure EVA in youth and to discuss challenges in translating these methods into clinical practice.

AB - Since the conceptualization of early vascular aging (EVA) in 2008, significant efforts have been made to develop and improve its assessment. Initially lead by the investigation of arterial stiffness through pulse wave velocity (PWV), several additional vascular aging biomarkers have gained prominence in recent years. Despite expanding literature addressing methodological concerns associated with these biomarkers in youth, a standardized approach for clinical evaluation of EVA remains elusive, leaving pertinent gaps in understanding the optimal methodology. This article, resulting from international consensus efforts from the Youth Vascular Consortium, aims to provide an updated overview of methods available to measure EVA in youth and to discuss challenges in translating these methods into clinical practice.

U2 - 10.1097/HJH.0000000000004039

DO - 10.1097/HJH.0000000000004039

M3 - Review article

C2 - 40366131

SN - 1473-5598

JO - Journal of Hypertension

JF - Journal of Hypertension

ER -

Measuring early vascular aging in youth: An expert consensus document from the Youth Vascular Consortium

Sammanfattning

Bibliografisk information

Ämnesklassifikation (UKÄ)

FN:s Globala mål

Tillgång till dokument

Fingeravtryck

Projekt

Vascular Ageing and Arterial Stiffness in the Swedish Population

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