Sammanfattning
We demonstrate direct visualization of melting mapping of DNA stretched in nanoscale channels[1] using standard staining methods and epifluorescence microscopy to gain information on the local AT/GC ratio along large DNA molecules. Our development opens up a novel route to mapping of large-scale genomic variations.
Originalspråk | engelska |
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Sidor | 1516-1518 |
Antal sidor | 3 |
Status | Published - 2008 jan. 1 |
Evenemang | 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, USA Varaktighet: 2008 okt. 12 → 2008 okt. 16 |
Konferens
Konferens | 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 |
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Land/Territorium | USA |
Ort | San Diego, CA |
Period | 2008/10/12 → 2008/10/16 |