Forskningsoutput per år
Forskningsoutput per år
Sara Bachiller, Itzia Jiménez-Ferrer, Agnes Paulus, Yiyi Yang, Maria Swanberg, Tomas Deierborg, Antonio Boza-Serrano
Forskningsoutput: Tidskriftsbidrag › Översiktsartikel › Peer review
Microglia represent a specialized population of macrophages-like cells in the central nervous system (CNS) considered immune sentinels that are capable of orchestrating a potent inflammatory response. Microglia are also involved in synaptic organization, trophic neuronal support during development, phagocytosis of apoptotic cells in the developing brain, myelin turnover, control of neuronal excitability, phagocytic debris removal as well as brain protection and repair. Microglial response is pathology dependent and affects to immune, metabolic. In this review, we will shed light on microglial activation depending on the disease context and the influence of factors such as aging, environment or cell-to-cell interaction.
Originalspråk | engelska |
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Artikelnummer | 488 |
Tidskrift | Frontiers in Cellular Neuroscience |
Volym | 12 |
DOI | |
Status | Published - 2018 dec. 18 |
Forskningsoutput: Kapitel i bok/rapport/Conference proceeding › Kapitel samlingsverk › Forskning › Peer review