Migration and invasion of oral squamous carcinoma cells is promoted by WNT5A, a regulator of cancer progression.

Zdenka Prgomet, Lena Axelsson, Pia Lindberg, Tommy Andersson

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskriftPeer review

Sammanfattning

Oral squamous cell carcinoma (OSCC) constitutes 90% of all cancers in the oral cavity, and the prognosis for patients diagnosed with OSCC is still poor. The identification of novel therapeutic targets and prognostic markers for OSCC is therefore essential. Previous studies of OSCC revealed an increased expression of WNT5A in the tumor tissue. However, no functional studies of WNT5A-induced effects in OSCC have been performed.
Originalspråkengelska
Sidor (från-till)776-784
TidskriftJournal of Oral Pathology & Medicine
Volym44
Nummer10
DOI
StatusPublished - 2015

Ämnesklassifikation (UKÄ)

  • Cancer och onkologi

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