Modeling of the SLIPI technique with the large scatterer approximation of the RTE

To overcome the blur when visualizing of the interior of a turbid media by means light-based methods, a technique called Structured Laser Illumination Planar Imaging (SLIPI) is employed. The method is based on a 'light coding' strategy to distinguish between directly and multiply scattered light, allowing the intensity from the latter to be suppressed by post-processing data. In this paper, we explain the origin of the deviations between SLIPI measurements and the results obtained by the Bouguer-Beer law. The explanation employs the large scatterer approximation of the Radiative Transfer Equation. Our results indicate that forward-scattering can lead to deviations between experiments and theoretical predictions, especially when probing relatively large particles.