Multinodal high throughput acoustic trapping of exosomes from urine samples

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Sammanfattning

We report a new design of an acoustophoretic trapping device with greatly increased capacity and throughput, compared to current commercial systems. Acoustic trapping enables nanoparticle and exosome enrichment without the need for ultracentrifugation. The commercial acoustic trapping technology, AcouTrap (AcouSort AB), typically operates at flow rates < 50 μl/min which limits processing of larger samples. Using a larger capillary that supports an acoustic multi-node resonance, capacity and throughput was increased a factor 40 compared to AcouTrap. It was possible to capture and enrich exosomes from urine samples at 30 times higher flow rate than previously reported.

Originalspråkengelska
Titel på värdpublikation23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
FörlagChemical and Biological Microsystems Society
Sidor2-3
Antal sidor2
ISBN (elektroniskt)9781733419000
StatusPublished - 2019
Evenemang23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 - Basel, Schweiz
Varaktighet: 2019 okt. 272019 okt. 31

Publikationsserier

Namn23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019

Konferens

Konferens23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
Land/TerritoriumSchweiz
OrtBasel
Period2019/10/272019/10/31

Ämnesklassifikation (UKÄ)

  • Medicinsk laboratorie- och mätteknik
  • Cancer och onkologi

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