Optogenetic control of human neurons in organotypic brain cultures

My Andersson, Natalia Avaliani, Andreas Svensson, Jenny Wickham, Lars H. Pinborg, Bo Jespersen, Søren H. Christiansen, Johan Bengzon, David P D Woldbye, Merab Kokaia

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskriftPeer review

29 Citeringar (SciVal)

Sammanfattning

Optogenetics is one of the most powerful tools in neuroscience, allowing for selective control of specific neuronal populations in the brain of experimental animals, including mammals. We report, for the first time, the application of optogenetic tools to human brain tissue providing a proof-of-concept for the use of optogenetics in neuromodulation of human cortical and hippocampal neurons as a possible tool to explore network mechanisms and develop future therapeutic strategies.

Originalspråkengelska
Artikelnummer24818
TidskriftScientific Reports
Volym6
DOI
StatusPublished - 2016 apr 21

Ämnesklassifikation (UKÄ)

  • Neurologi

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