Patch testing with methylchloroisothiazolinone/methylisothiazolinone 200 ppm aq. detects significantly more contact allergy than 100 ppm. A multicentre study within the European Environmental and Contact Dermatitis Research Group.

Magnus Bruze; Marléne Isaksson; Birgitta Gruvberger; Klaus E Andersen; Margarida Gonçalo; An Goossens; Jeanne D Johansen; Howard I Maibach; Thomas Rustemeyer; Christophe-J Le Coz; Ian R White

doi:10.1111/cod.12241

Patch testing with methylchloroisothiazolinone/methylisothiazolinone 200 ppm aq. detects significantly more contact allergy than 100 ppm. A multicentre study within the European Environmental and Contact Dermatitis Research Group.

Magnus Bruze, Marléne Isaksson, Birgitta Gruvberger, Klaus E Andersen, Margarida Gonçalo, An Goossens, Jeanne D Johansen, Howard I Maibach, Thomas Rustemeyer, Christophe-J Le Coz, Ian R White

Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

Sammanfattning

Methylchloroisothiazolinone (MCI) and methylisothiazolinone (MI) are the active ingredients in commonly used preservative systems (e.g. Kathon CG(®) ). MCI/MI is present in the European baseline patch test series at 100 ppm aq. Since 1986, 200 ppm (dose 0.006 mg/cm(2) ) has been used in Sweden without causing skin irritation. Centres in Spain, the United Kingdom and Ireland have also used 200 ppm in their baseline series.

Originalspråk	engelska
Sidor (från-till)	31-34
Tidskrift	Contact Dermatitis
Volym	71
Nummer	1
DOI	https://doi.org/10.1111/cod.12241
Status	Published - 2014

Bibliografisk information

The information about affiliations in this record was updated in December 2015.
The record was previously connected to the following departments: Occupational and Environmental Dermatology Unit (013241310), Pediatrics/Urology/Gynecology/Endocrinology (013240400)

Ämnesklassifikation (UKÄ)

Dermatologi och venereologi

Tillgång till dokument

10.1111/cod.12241

http://www.ncbi.nlm.nih.gov/pubmed/24712418?dopt=Abstract

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Citera det här

Bruze, M., Isaksson, M., Gruvberger, B., Andersen, K. E., Gonçalo, M., Goossens, A., Johansen, J. D., Maibach, H. I., Rustemeyer, T., Le Coz, C.-J., & White, I. R. (2014). Patch testing with methylchloroisothiazolinone/methylisothiazolinone 200 ppm aq. detects significantly more contact allergy than 100 ppm. A multicentre study within the European Environmental and Contact Dermatitis Research Group. Contact Dermatitis, 71(1), 31-34. https://doi.org/10.1111/cod.12241

@article{9dd4771f0b224f5b9a97c869d629ffb7,

title = "Patch testing with methylchloroisothiazolinone/methylisothiazolinone 200 ppm aq. detects significantly more contact allergy than 100 ppm. A multicentre study within the European Environmental and Contact Dermatitis Research Group.",

abstract = "Methylchloroisothiazolinone (MCI) and methylisothiazolinone (MI) are the active ingredients in commonly used preservative systems (e.g. Kathon CG({\textregistered}) ). MCI/MI is present in the European baseline patch test series at 100 ppm aq. Since 1986, 200 ppm (dose 0.006 mg/cm(2) ) has been used in Sweden without causing skin irritation. Centres in Spain, the United Kingdom and Ireland have also used 200 ppm in their baseline series.",

author = "Magnus Bruze and Marl{\'e}ne Isaksson and Birgitta Gruvberger and Andersen, {Klaus E} and Margarida Gon{\c c}alo and An Goossens and Johansen, {Jeanne D} and Maibach, {Howard I} and Thomas Rustemeyer and {Le Coz}, Christophe-J and White, {Ian R}",

note = "The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Occupational and Environmental Dermatology Unit (013241310), Pediatrics/Urology/Gynecology/Endocrinology (013240400)",

year = "2014",

doi = "10.1111/cod.12241",

language = "English",

volume = "71",

pages = "31--34",

journal = "Contact Dermatitis",

issn = "0105-1873",

publisher = "Wiley-Blackwell",

number = "1",

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Bruze, M , Isaksson, M, Gruvberger, B, Andersen, KE, Gonçalo, M, Goossens, A, Johansen, JD, Maibach, HI, Rustemeyer, T, Le Coz, C-J & White, IR 2014, 'Patch testing with methylchloroisothiazolinone/methylisothiazolinone 200 ppm aq. detects significantly more contact allergy than 100 ppm. A multicentre study within the European Environmental and Contact Dermatitis Research Group.', Contact Dermatitis, vol. 71, nr. 1, s. 31-34. https://doi.org/10.1111/cod.12241

Patch testing with methylchloroisothiazolinone/methylisothiazolinone 200 ppm aq. detects significantly more contact allergy than 100 ppm. A multicentre study within the European Environmental and Contact Dermatitis Research Group. / Bruze, Magnus ; Isaksson, Marléne; Gruvberger, Birgitta et al.
I: Contact Dermatitis, Vol. 71, Nr. 1, 2014, s. 31-34.

Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

TY - JOUR

T1 - Patch testing with methylchloroisothiazolinone/methylisothiazolinone 200 ppm aq. detects significantly more contact allergy than 100 ppm. A multicentre study within the European Environmental and Contact Dermatitis Research Group.

AU - Bruze, Magnus

AU - Isaksson, Marléne

AU - Gruvberger, Birgitta

AU - Andersen, Klaus E

AU - Gonçalo, Margarida

AU - Goossens, An

AU - Johansen, Jeanne D

AU - Maibach, Howard I

AU - Rustemeyer, Thomas

AU - Le Coz, Christophe-J

AU - White, Ian R

N1 - The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Occupational and Environmental Dermatology Unit (013241310), Pediatrics/Urology/Gynecology/Endocrinology (013240400)

PY - 2014

Y1 - 2014

N2 - Methylchloroisothiazolinone (MCI) and methylisothiazolinone (MI) are the active ingredients in commonly used preservative systems (e.g. Kathon CG(®) ). MCI/MI is present in the European baseline patch test series at 100 ppm aq. Since 1986, 200 ppm (dose 0.006 mg/cm(2) ) has been used in Sweden without causing skin irritation. Centres in Spain, the United Kingdom and Ireland have also used 200 ppm in their baseline series.

AB - Methylchloroisothiazolinone (MCI) and methylisothiazolinone (MI) are the active ingredients in commonly used preservative systems (e.g. Kathon CG(®) ). MCI/MI is present in the European baseline patch test series at 100 ppm aq. Since 1986, 200 ppm (dose 0.006 mg/cm(2) ) has been used in Sweden without causing skin irritation. Centres in Spain, the United Kingdom and Ireland have also used 200 ppm in their baseline series.

U2 - 10.1111/cod.12241

DO - 10.1111/cod.12241

M3 - Article

C2 - 24712418

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VL - 71

SP - 31

EP - 34

JO - Contact Dermatitis

JF - Contact Dermatitis

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ER -