Sammanfattning
Diffusion of proteins on length scales of their size is crucial for understanding the machinery of living cells. X-ray photon correlation spectroscopy (XPCS) is currently the only way to access long-time collective diffusion on these length scales, but radiation damage so far limits the use in biological systems. We apply a new approach to use XPCS to measure cage relaxation in crowded α-crystallin solutions. This allows us to correct for radiation effects, obtain missing information on long time diffusion, and support the fundamental analogy between protein and colloid dynamical arrest.
Originalspråk | engelska |
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Artikelnummer | 238001 |
Antal sidor | 6 |
Tidskrift | Physical Review Letters |
Volym | 129 |
Nummer | 23 |
DOI | |
Status | Published - 2022 dec. 2 |
Ämnesklassifikation (UKÄ)
- Fysikalisk kemi
- Biofysik