Proliferation and benevolence—A framework for dissecting the mechanisms of microbial virulence and health promotion

Kristofer Wollein Waldetoft, Lars Råberg, Rolf Lood

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskriftPeer review

1 Citering (SciVal)

Sammanfattning

Key topics in the study of host–microbe interactions—such as the prevention of drug resistance and the exploitation of beneficial effects of bacteria—would benefit from concerted efforts with both mechanistic and evolutionary approaches. But due to differences in intellectual traditions, insights gained in one field rarely benefit the other. Here, we develop a conceptual and analytical framework for the integrated study of host–microbe interactions. This framework partitions the health effects of microbes and the effector molecules they produce into components with different evolutionary implications. It thereby facilitates the prediction of evolutionary responses to inhibition and exploitation of specific molecular mechanisms.

Originalspråkengelska
Sidor (från-till)879-888
Antal sidor10
TidskriftEvolutionary Applications
Volym13
Utgåva5
Tidigt onlinedatum2020 mar 14
DOI
StatusPublished - 2020 maj

Ämnesklassifikation (UKÄ)

  • Farmaceutisk vetenskap
  • Bioinformatik och systembiologi

Fingeravtryck

Utforska forskningsämnen för ”Proliferation and benevolence—A framework for dissecting the mechanisms of microbial virulence and health promotion”. Tillsammans bildar de ett unikt fingeravtryck.

Citera det här