Prophylaxis Escalation in Severe von Willebrand Disease: A Prospective Study from the von Willebrand Disease Prophylaxis Network.

T Abshire; J Cox-Gill; C L Kempton; F W G Leebeek; M Carcao; P Kouides; S Donfield; Erik Berntorp

doi:10.1111/jth.12995

Prophylaxis Escalation in Severe von Willebrand Disease: A Prospective Study from the von Willebrand Disease Prophylaxis Network.

T Abshire, J Cox-Gill, C L Kempton, F W G Leebeek, M Carcao, P Kouides, S Donfield, Erik Berntorp

Klinisk koagulationsmedicin, Malmö

Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

Sammanfattning

Treatment of mucosal bleeding (epistaxis, gastrointestinal and menorrhagia) and joint bleeding remains problematic in clinically severe von Willebrand Disease (VWD). Patients are often unresponsive to treatment (e.g. desmopressin or antifibrinolytic therapy) and may require von Willebrand (VW) factor replacement therapy. There are little data on the use of prophylaxis in VWD and none applied in a prospective, treatment escalation design.

Originalspråk	engelska
Sidor (från-till)	1585-1589
Tidskrift	Journal of Thrombosis and Haemostasis
Volym	13
Nummer	9
DOI	https://doi.org/10.1111/jth.12995
Status	Published - 2015

Ämnesklassifikation (UKÄ)

Kardiologi

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10.1111/jth.12995

http://www.ncbi.nlm.nih.gov/pubmed/25930155?dopt=Abstract

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title = "Prophylaxis Escalation in Severe von Willebrand Disease: A Prospective Study from the von Willebrand Disease Prophylaxis Network.",

abstract = "Treatment of mucosal bleeding (epistaxis, gastrointestinal and menorrhagia) and joint bleeding remains problematic in clinically severe von Willebrand Disease (VWD). Patients are often unresponsive to treatment (e.g. desmopressin or antifibrinolytic therapy) and may require von Willebrand (VW) factor replacement therapy. There are little data on the use of prophylaxis in VWD and none applied in a prospective, treatment escalation design.",

author = "T Abshire and J Cox-Gill and Kempton, {C L} and Leebeek, {F W G} and M Carcao and P Kouides and S Donfield and Erik Berntorp",

year = "2015",

doi = "10.1111/jth.12995",

language = "English",

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AU - Abshire, T

AU - Cox-Gill, J

AU - Kempton, C L

AU - Leebeek, F W G

AU - Carcao, M

AU - Kouides, P

AU - Donfield, S

AU - Berntorp, Erik

PY - 2015

Y1 - 2015

N2 - Treatment of mucosal bleeding (epistaxis, gastrointestinal and menorrhagia) and joint bleeding remains problematic in clinically severe von Willebrand Disease (VWD). Patients are often unresponsive to treatment (e.g. desmopressin or antifibrinolytic therapy) and may require von Willebrand (VW) factor replacement therapy. There are little data on the use of prophylaxis in VWD and none applied in a prospective, treatment escalation design.

AB - Treatment of mucosal bleeding (epistaxis, gastrointestinal and menorrhagia) and joint bleeding remains problematic in clinically severe von Willebrand Disease (VWD). Patients are often unresponsive to treatment (e.g. desmopressin or antifibrinolytic therapy) and may require von Willebrand (VW) factor replacement therapy. There are little data on the use of prophylaxis in VWD and none applied in a prospective, treatment escalation design.

U2 - 10.1111/jth.12995

DO - 10.1111/jth.12995

M3 - Article

C2 - 25930155

SN - 1538-7933

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JO - Journal of Thrombosis and Haemostasis

JF - Journal of Thrombosis and Haemostasis

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Prophylaxis Escalation in Severe von Willebrand Disease: A Prospective Study from the von Willebrand Disease Prophylaxis Network.

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Ämnesklassifikation (UKÄ)

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