Rectal washout during abdominoperineal resection for rectal cancer has no impact on the oncological outcome

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskriftPeer review

Sammanfattning

Aim
Intraoperative rectal washout is performed to eliminate exfoliated intraluminal cancer cells and thereby decrease the risk of local recurrence. Rectal washout in abdominoperineal resection has not been studied. The aim of this study was to assess the oncological outcome after rectal washout in abdominoperineal resection for rectal cancer and to find evidence as to whether rectal washout should be performed or not.

Method
Data for all patients registered in the Swedish Colorectal Cancer Registry who underwent elective surgery with abdominoperineal resection for rectal cancer (TNM Stages I–III) between 2007 and 2013 were analysed using multivariable analysis.

Results
No significant differences were shown between the rectal washout group and the no rectal washout group for local recurrence [10/265 (3.8%) vs. 87/2160 (4.0%), p = 0.84], distant metastasis [51/265 (19.2%) vs. 476/2160 (22.0%), p = 0.29] or overall recurrence [53/265 (20.0%) vs. 505/2160 (23.4%), p = 0.21]. In multivariable analysis, rectal washout did not significantly affect the oncological outcome in terms of local recurrence, distant metastasis, overall recurrence or 5-year overall or relative survival.

Conclusion
Our results do not support routine rectal washout during abdominoperineal resection in order to improve the oncological outcome.

What does this paper add to the literature?
This is the first study to investigate the oncological outcome after rectal washout during abdominoperineal resection for rectal cancer in order to find evidence as to whether rectal washout should be performed or not.
Originalspråkengelska
TidskriftColorectal Disease
DOI
StatusE-pub ahead of print - 2021 nov. 2

Ämnesklassifikation (UKÄ)

  • Kirurgi
  • Cancer och onkologi

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