Reovirus type 1 associated with meningitis

Hugo Johansson, Tomas Sveger, Karin Ahlfors, Jarl Ekstrand, Lennart Svensson

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskriftPeer review

38 Citeringar (SciVal)

Sammanfattning

A previously healthy 3-month-old girl presented with symptoms of meningitis, diarrhoea, vomiting and fever. Green monkey kidney (GMK) cells inoculated with cerebrospinal fluid (CSF) revealed reovirus-like particles by electron microscopy. RNA-gel electrophoresis, immunofluorescence and virus neutralization identified the pathogen isolated from CSF as reovirus type 1. Antibody determination by immunofluorescence of paired sera showed a significant antibody titre rise to the CSF isolate and neutralization test revealed a greater than 4-fold antibody titre rise to the CSF isolate. The CSF isolate was also neutralized by reovirus type 1 antibodies. This report represents one of a few associating reovirus with CNS symptoms in humans.
Originalspråkengelska
Sidor (från-till)117-120
TidskriftScandinavian Journal of Infectious Diseases
Volym28
Utgåva2
DOI
StatusPublished - 1996

Ämnesklassifikation (UKÄ)

  • Infektionsmedicin

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