TY - JOUR
T1 - Risk of pediatric celiac disease according to HLA haplotype and country.
AU - Liu, Edwin
AU - Lee, Hye-Seung
AU - Andrén Aronsson, Carin
AU - Hagopian, William A
AU - Koletzko, Sibylle
AU - Rewers, Marian J
AU - Eisenbarth, George S
AU - Bingley, Polly J
AU - Bonifacio, Ezio
AU - Simell, Ville
AU - Agardh, Daniel
PY - 2014
Y1 - 2014
N2 - The presence of HLA haplotype DR3-DQ2 or DR4-DQ8 is associated with an increased risk of celiac disease. In addition, nearly all children with celiac disease have serum antibodies against tissue transglutaminase (tTG).
AB - The presence of HLA haplotype DR3-DQ2 or DR4-DQ8 is associated with an increased risk of celiac disease. In addition, nearly all children with celiac disease have serum antibodies against tissue transglutaminase (tTG).
KW - Antibodies: blood
KW - Autoimmune Diseases: epidemiology
KW - Autoimmune Diseases: genetics
KW - Celiac Disease: epidemiology
KW - Celiac Disease: genetics
KW - Europe: epidemiology
KW - HLA-DQ Antigens: genetics
KW - HLA-DR3 Antigen: genetics
KW - HLA-DR4 Antigen: genetics
KW - Transglutaminases: immunology
KW - United States: epidemiology
U2 - 10.1056/NEJMoa1313977
DO - 10.1056/NEJMoa1313977
M3 - Article
C2 - 24988556
SN - 0028-4793
VL - 371
SP - 42
EP - 49
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 1
ER -