Rutinmässig screening med APTT är inte indicerad före operation

Li Bian, Fariba Baghaei, Jovan Antovic, Inger Fagerberg Blixter, Andreas Hillarp, Karin Strandberg, David Willman, Tomas L Lindahl

Forskningsoutput: TidskriftsbidragÖversiktsartikelPeer review


Activated partial thromboplastin time (APTT) is widely practiced in preoperative screening. The value of using this test to predict the risk of perioperative bleeding is not well documented in Sweden. In this article, a literature review is performed to determine whether unselected APTT testing can predict abnormal perioperative bleeding. The current literature does not support coagulation screening with APTT in routine perioperative bleeding assessment, as preoperative screening with APTT has a low sensitivity for detection of clinically significant bleeding disorder. While a comprehensive bleeding history is crucial, the APTT test should only be performed on patients with a history of increased bleeding tendency. The conclusion of this literature review is that patients with a negative bleeding history do not require routine screening with APTT prior to surgery, which, if implemented, would lead to a more cost-effective perioperative routine.

Bidragets översatta titel Routine screening with APTT is not indicated before surgery
StatusPublished - 2022 juni 17
Externt publiceradJa

Ämnesklassifikation (UKÄ)

  • Hematologi

Fria nyckelord

  • Blood Coagulation Tests
  • Hemorrhage
  • Humans
  • Mass Screening
  • Partial Thromboplastin Time
  • Sweden


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