Sex-Specific Effects of Adiponectin on Carotid Intima-Media Thickness and Incident Cardiovascular Disease.

Jonas Persson; Rona J Strawbridge; Olga McLeod; Karl Gertow; Angela Silveira; Damiano Baldassarre; Natalie Van Zuydam; Sonia Shah; Cristiano Fava; Stefan Gustafsson; Fabrizio Veglia; Bengt Sennblad; Malin Larsson; Maria Sabater-Lleal; Karin Leander; Bruna Gigante; Adam Tabak; Mika Kivimaki; Jussi Kauhanen; Rainer Rauramaa; Andries J Smit; Elmo Mannarino; Philippe Giral; Steve E Humphries; Elena Tremoli; Ulf de Faire; Lars Lind; Erik Ingelsson; Bo Hedblad; Olle Melander; Meena Kumari; Aroon Hingorani; Andrew D Morris; Colin N A Palmer; Pia Lundman; John Öhrvik; Stefan Söderberg; Anders Hamsten

doi:10.1161/JAHA.115.001853

Sex-Specific Effects of Adiponectin on Carotid Intima-Media Thickness and Incident Cardiovascular Disease.

Jonas Persson, Rona J Strawbridge, Olga McLeod, Karl Gertow, Angela Silveira, Damiano Baldassarre, Natalie Van Zuydam, Sonia Shah, Cristiano Fava, Stefan Gustafsson, Fabrizio Veglia, Bengt Sennblad, Malin Larsson, Maria Sabater-Lleal, Karin Leander, Bruna Gigante, Adam Tabak, Mika Kivimaki, Jussi Kauhanen, Rainer RauramaaAndries J Smit, Elmo Mannarino, Philippe Giral, Steve E Humphries, Elena Tremoli, Ulf de Faire, Lars Lind, Erik Ingelsson, Bo Hedblad, Olle Melander, Meena Kumari, Aroon Hingorani, Andrew D Morris, Colin N A Palmer, Pia Lundman, John Öhrvik, Stefan Söderberg, Anders Hamsten

Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

27 Citeringar (SciVal)

41 Nedladdningar (Pure)

Sammanfattning

Plasma adiponectin levels have previously been inversely associated with carotid intima-media thickness (IMT), a marker of subclinical atherosclerosis. In this study, we used a sex-stratified Mendelian randomization approach to investigate whether adiponectin has a causal protective influence on IMT.

Originalspråk	engelska
Artikelnummer	e001853
Tidskrift	Journal of the American Heart Association
Volym	4
Utgåva	8
DOI	https://doi.org/10.1161/JAHA.115.001853
Status	Published - 2015

Ämnesklassifikation (UKÄ)

Kardiologi

Tillgång till dokument

10.1161/JAHA.115.001853

Wiley_Persson

http://www.ncbi.nlm.nih.gov/pubmed/26276317?dopt=Abstract

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Persson, J., Strawbridge, R. J., McLeod, O., Gertow, K., Silveira, A., Baldassarre, D., Van Zuydam, N., Shah, S., Fava, C., Gustafsson, S., Veglia, F., Sennblad, B., Larsson, M., Sabater-Lleal, M., Leander, K., Gigante, B., Tabak, A., Kivimaki, M., Kauhanen, J., ... Hamsten, A. (2015). Sex-Specific Effects of Adiponectin on Carotid Intima-Media Thickness and Incident Cardiovascular Disease. Journal of the American Heart Association, 4(8), [e001853]. https://doi.org/10.1161/JAHA.115.001853

Persson, Jonas ; Strawbridge, Rona J ; McLeod, Olga ; Gertow, Karl ; Silveira, Angela ; Baldassarre, Damiano ; Van Zuydam, Natalie ; Shah, Sonia ; Fava, Cristiano ; Gustafsson, Stefan ; Veglia, Fabrizio ; Sennblad, Bengt ; Larsson, Malin ; Sabater-Lleal, Maria ; Leander, Karin ; Gigante, Bruna ; Tabak, Adam ; Kivimaki, Mika ; Kauhanen, Jussi ; Rauramaa, Rainer ; Smit, Andries J ; Mannarino, Elmo ; Giral, Philippe ; Humphries, Steve E ; Tremoli, Elena ; de Faire, Ulf ; Lind, Lars ; Ingelsson, Erik ; Hedblad, Bo ; Melander, Olle ; Kumari, Meena ; Hingorani, Aroon ; Morris, Andrew D ; Palmer, Colin N A ; Lundman, Pia ; Öhrvik, John ; Söderberg, Stefan ; Hamsten, Anders. / Sex-Specific Effects of Adiponectin on Carotid Intima-Media Thickness and Incident Cardiovascular Disease. I: Journal of the American Heart Association. 2015 ; Vol. 4, Nr. 8.

@article{cb16c0d27d1f422ba45a4782a9aa5155,

title = "Sex-Specific Effects of Adiponectin on Carotid Intima-Media Thickness and Incident Cardiovascular Disease.",

abstract = "Plasma adiponectin levels have previously been inversely associated with carotid intima-media thickness (IMT), a marker of subclinical atherosclerosis. In this study, we used a sex-stratified Mendelian randomization approach to investigate whether adiponectin has a causal protective influence on IMT.",

author = "Jonas Persson and Strawbridge, {Rona J} and Olga McLeod and Karl Gertow and Angela Silveira and Damiano Baldassarre and {Van Zuydam}, Natalie and Sonia Shah and Cristiano Fava and Stefan Gustafsson and Fabrizio Veglia and Bengt Sennblad and Malin Larsson and Maria Sabater-Lleal and Karin Leander and Bruna Gigante and Adam Tabak and Mika Kivimaki and Jussi Kauhanen and Rainer Rauramaa and Smit, {Andries J} and Elmo Mannarino and Philippe Giral and Humphries, {Steve E} and Elena Tremoli and {de Faire}, Ulf and Lars Lind and Erik Ingelsson and Bo Hedblad and Olle Melander and Meena Kumari and Aroon Hingorani and Morris, {Andrew D} and Palmer, {Colin N A} and Pia Lundman and John {\"O}hrvik and Stefan S{\"o}derberg and Anders Hamsten",

year = "2015",

doi = "10.1161/JAHA.115.001853",

language = "English",

volume = "4",

journal = "Journal of the American Heart Association",

issn = "2047-9980",

publisher = "Wiley-Blackwell",

number = "8",

}

Persson, J, Strawbridge, RJ, McLeod, O, Gertow, K, Silveira, A, Baldassarre, D, Van Zuydam, N, Shah, S, Fava, C, Gustafsson, S, Veglia, F, Sennblad, B, Larsson, M, Sabater-Lleal, M, Leander, K, Gigante, B, Tabak, A, Kivimaki, M, Kauhanen, J, Rauramaa, R, Smit, AJ, Mannarino, E, Giral, P, Humphries, SE, Tremoli, E, de Faire, U, Lind, L, Ingelsson, E, Hedblad, B , Melander, O, Kumari, M, Hingorani, A, Morris, AD, Palmer, CNA, Lundman, P, Öhrvik, J, Söderberg, S & Hamsten, A 2015, 'Sex-Specific Effects of Adiponectin on Carotid Intima-Media Thickness and Incident Cardiovascular Disease.', Journal of the American Heart Association, vol. 4, nr. 8, e001853. https://doi.org/10.1161/JAHA.115.001853

Sex-Specific Effects of Adiponectin on Carotid Intima-Media Thickness and Incident Cardiovascular Disease. / Persson, Jonas; Strawbridge, Rona J; McLeod, Olga; Gertow, Karl; Silveira, Angela; Baldassarre, Damiano; Van Zuydam, Natalie; Shah, Sonia; Fava, Cristiano; Gustafsson, Stefan; Veglia, Fabrizio; Sennblad, Bengt; Larsson, Malin; Sabater-Lleal, Maria; Leander, Karin; Gigante, Bruna; Tabak, Adam; Kivimaki, Mika; Kauhanen, Jussi; Rauramaa, Rainer; Smit, Andries J; Mannarino, Elmo; Giral, Philippe; Humphries, Steve E; Tremoli, Elena; de Faire, Ulf; Lind, Lars; Ingelsson, Erik; Hedblad, Bo ; Melander, Olle; Kumari, Meena; Hingorani, Aroon; Morris, Andrew D; Palmer, Colin N A; Lundman, Pia; Öhrvik, John; Söderberg, Stefan; Hamsten, Anders.

I: Journal of the American Heart Association, Vol. 4, Nr. 8, e001853, 2015.

Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

TY - JOUR

T1 - Sex-Specific Effects of Adiponectin on Carotid Intima-Media Thickness and Incident Cardiovascular Disease.

AU - Persson, Jonas

AU - Strawbridge, Rona J

AU - McLeod, Olga

AU - Gertow, Karl

AU - Silveira, Angela

AU - Baldassarre, Damiano

AU - Van Zuydam, Natalie

AU - Shah, Sonia

AU - Fava, Cristiano

AU - Gustafsson, Stefan

AU - Veglia, Fabrizio

AU - Sennblad, Bengt

AU - Larsson, Malin

AU - Sabater-Lleal, Maria

AU - Leander, Karin

AU - Gigante, Bruna

AU - Tabak, Adam

AU - Kivimaki, Mika

AU - Kauhanen, Jussi

AU - Rauramaa, Rainer

AU - Smit, Andries J

AU - Mannarino, Elmo

AU - Giral, Philippe

AU - Humphries, Steve E

AU - Tremoli, Elena

AU - de Faire, Ulf

AU - Lind, Lars

AU - Ingelsson, Erik

AU - Hedblad, Bo

AU - Melander, Olle

AU - Kumari, Meena

AU - Hingorani, Aroon

AU - Morris, Andrew D

AU - Palmer, Colin N A

AU - Lundman, Pia

AU - Öhrvik, John

AU - Söderberg, Stefan

AU - Hamsten, Anders

PY - 2015

Y1 - 2015

N2 - Plasma adiponectin levels have previously been inversely associated with carotid intima-media thickness (IMT), a marker of subclinical atherosclerosis. In this study, we used a sex-stratified Mendelian randomization approach to investigate whether adiponectin has a causal protective influence on IMT.

AB - Plasma adiponectin levels have previously been inversely associated with carotid intima-media thickness (IMT), a marker of subclinical atherosclerosis. In this study, we used a sex-stratified Mendelian randomization approach to investigate whether adiponectin has a causal protective influence on IMT.

U2 - 10.1161/JAHA.115.001853

DO - 10.1161/JAHA.115.001853

M3 - Article

C2 - 26276317

VL - 4

JO - Journal of the American Heart Association

JF - Journal of the American Heart Association

SN - 2047-9980

IS - 8

M1 - e001853

ER -

Sex-Specific Effects of Adiponectin on Carotid Intima-Media Thickness and Incident Cardiovascular Disease.

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