Sleep duration and risk of cancer incidence and mortality: A pooled analysis of six population-based cohorts in Japan

Calistus Wilunda, Sarah Krull Abe, Thomas Svensson, Norie Sawada, Shoichiro Tsugane, Keiko Wada, Chisato Nagata, Takashi Kimura, Akiko Tamakoshi, Yumi Sugawara, Ichiro Tsuji, Hidemi Ito, Tetsuhisa Kitamura, Ritsu Sakata, Tetsuya Mizoue, Keitaro Matsuo, Keitaro Tanaka, Yingsong Lin, Manami Inoue, Research Group for the Development and Evaluation of Cancer Prevention Strategies in Japan

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskriftPeer review

1 Citering (SciVal)

Sammanfattning

Sleep duration is emerging as an important modifiable risk factor for morbidity and mortality. We assessed the association between sleep duration and cancer incidence and mortality among Japanese adults using data from six population-based cohorts with 271 694 participants. During a total follow-up period of about 5.9 million person-years, we identified 40 751 incident cancer cases and 18 323 cancer deaths. We computed study-specific hazard ratios (HRs) and 95% confidence intervals (CIs) using Cox proportional hazards regression models and pooled the estimates using random-effects meta-analysis. Sleep duration of ≥10 hours (vs 7 hours) was associated with increased risk of cancer incidence among women (HR 1.19, 95% CI 1.02-1.38), but not men, and increased risk of cancer mortality among men (HR 1.18, 95% CI 1.00-1.39) and women (HR 1.44, 95% CI 1.20-1.73). Sleep duration of ≤5 hours (vs 7 hours) was not associated with cancer incidence and mortality. However, among postmenopausal women, sleep durations of both ≤5 and ≥10 hours (vs 7 hours) were associated with an increased risk of cancer mortality. Among Japanese adults, sleep duration of ≥10 hours is associated with increased risk of cancer incidence and mortality among women and cancer mortality among men.

Originalspråkengelska
Sidor (från-till)1-13
TidskriftInternational Journal of Cancer
DOI
StatusE-pub ahead of print - 2022

Bibliografisk information

© 2022 UICC.

Ämnesklassifikation (UKÄ)

  • Cancer och onkologi

Fingeravtryck

Utforska forskningsämnen för ”Sleep duration and risk of cancer incidence and mortality: A pooled analysis of six population-based cohorts in Japan”. Tillsammans bildar de ett unikt fingeravtryck.

Citera det här