Stochastic aspects of transmitter release and bioenergetic dysfunction in isolated nerve terminals

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Sammanfattning

Synaptosomes (isolated nerve terminals) have been studied for more than 40 years. The preparation allows aspects of transmitter metabolism and release to be studied ex vivo from specific brain regions of animals of any age. Conditions can be devised to enable the terminals to fire spontaneous action potentials, allowing the presynaptic control of glutamate exocytosis to be studied. Recent developments have greatly increased the sensitivity with which the bioenergetics of the intra-synaptosomal mitochondria can be investigated.
Originalspråkengelska
Titel på värdpublikationBiochemical Society Transactions
FörlagPortland Press
Sidor457-459
Volym38
DOI
StatusPublished - 2010
EvenemangConference on Synaptopathies - Dysfunction of Synaptic Function - Newquay, England
Varaktighet: 2009 sep. 22009 sep. 4

Publikationsserier

Namn
Volym38
ISSN (tryckt)0300-5127
ISSN (elektroniskt)1470-8752

Konferens

KonferensConference on Synaptopathies - Dysfunction of Synaptic Function
Period2009/09/022009/09/04

Bibliografisk information

The information about affiliations in this record was updated in December 2015.
The record was previously connected to the following departments: Neuronal Survival (013212041)

Ämnesklassifikation (UKÄ)

  • Biokemi och molekylärbiologi

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