Studies on intrinsic and extrinsic sources of variability in pharmacokinetics and pharmacodynamics

Pharmacology, Toxicology and Pharmaceutical Science

• Pharmacokinetics 100%
• Pharmacodynamics 100%
• Bioavailability 80%
• Desmopressin 60%
• Prevalence 40%
• Ciclosporin 40%
• Pharmacotherapy 20%
• Fat 20%
• Hydration 20%
• Pharmacokinetic Parameter 20%
• Drug Metabolism 20%
• Excipient 20%

Biochemistry, Genetics and Molecular Biology

• Pharmacodynamics 100%
• Pharmacokinetics 100%
• Gene 66%
• Desmopressin 50%
• Lipid 33%
• Haplotype 33%
• Genetic Divergence 16%
• Genotyping 16%
• Fat 16%
• Single Nucleotide Polymorphism 16%
• Exon 16%
• Drug Response 16%
• Hydration 16%
• Drug Transport 16%

Neuroscience

• Gene 66%
• Ethnicity 33%
• Genotype 16%
• Polymorphism 16%