Synthesis of water-dispersible photoluminescent silicon nanoparticles and their use in biological fluorescent imaging

Qi Wang, Hongjun Ni, Annette Pietzsch, Franz Hennies, Yongping Bao, Yimin Chao

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskriftPeer review

43 Citeringar (SciVal)

Sammanfattning

Water-dispersible silicon nanoparticles (Si-NPs) are desirable for applications in biological techniques. A simplified method to synthesize such particles is reported here. The resulting Si-NPs are water-dispersible and luminescent. Under the excitation of UV light, the Si-NPs emit strong red light with a peak maximum at 606 nm and a quantum yield of 6%. They are highly stable, and remain so over several weeks. Fourier Transform Infrared (FTIR) spectroscopy shows a visible Si-CH2 scissoring vibration mode. Furthermore, the surface chemical bondings were confirmed by X-ray photoelectron spectroscopy (XPS). In the Si2p and C1s core levels, Si-C components are observed. The diameters of the synthesized Si-NPS as measured by atomic force microscope (AFM) are approximately 5 nm. Furthermore, the nanoparticles can be taken up by cultured cells. Fluorescence images of Si-NPs within MCF-7 human breast cancer cells show they are distributed throughout the cell tissue.
Originalspråkengelska
Sidor (från-till)405-413
TidskriftJournal of Nanoparticle Research
Volym13
Utgåva1
DOI
StatusPublished - 2011

Ämnesklassifikation (UKÄ)

  • Nanoteknik

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