TCF7L2 type 2 diabetes risk variant, lifestyle factors, and incidence of prostate cancer.

Isabel Drake; Peter Wallström; George Hindy; Ulrika Ericson; Bo Gullberg; Anders Bjartell; Emily Sonestedt; Marju Orho-Melander; Elisabet Wirfält

doi:10.1002/pros.22832

TCF7L2 type 2 diabetes risk variant, lifestyle factors, and incidence of prostate cancer.

Isabel Drake, Peter Wallström, George Hindy, Ulrika Ericson, Bo Gullberg, Anders Bjartell, Emily Sonestedt, Marju Orho-Melander, Elisabet Wirfält

Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

Sammanfattning

Variation in transcription factor 7-like 2 (TCF7L2), the strongest genetic risk factor for type 2 diabetes (T2D), may play a role in prostate cancer (PCa) depending on lifestyle factors. The aims of this study were to determine if TCF7L2 rs7903146 is associated with risk of PCa and if the association is modified by lifestyle factors independently of T2D status.

Originalspråk	engelska
Sidor (från-till)	1161-1170
Tidskrift	The Prostate
Volym	74
Nummer	12
DOI	https://doi.org/10.1002/pros.22832
Status	Published - 2014

FN:s Globala mål

Denna forskningsoutput relaterar till följande Globala mål

SDG 3 – God hälsa och välbefinnande

Ämnesklassifikation (UKÄ)

Gynekologi, obstetrik och reproduktionsmedicin

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10.1002/pros.22832

http://www.ncbi.nlm.nih.gov/pubmed/24961829?dopt=Abstract

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Link to publication in Scopus

Diabetes mellitus and risk of prostate cancer - A focus on shared risk factors and survivor bias
Drake, I., 2014, Department of Clinical Sciences, Lund University. 106 s.
Forskningsoutput: Avhandling › Doktorsavhandling (sammanläggning)

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title = "TCF7L2 type 2 diabetes risk variant, lifestyle factors, and incidence of prostate cancer.",

abstract = "Variation in transcription factor 7-like 2 (TCF7L2), the strongest genetic risk factor for type 2 diabetes (T2D), may play a role in prostate cancer (PCa) depending on lifestyle factors. The aims of this study were to determine if TCF7L2 rs7903146 is associated with risk of PCa and if the association is modified by lifestyle factors independently of T2D status.",

author = "Isabel Drake and Peter Wallstr{\"o}m and George Hindy and Ulrika Ericson and Bo Gullberg and Anders Bjartell and Emily Sonestedt and Marju Orho-Melander and Elisabet Wirf{\"a}lt",

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volume = "74",

pages = "1161--1170",

journal = "The Prostate",

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AU - Drake, Isabel

AU - Wallström, Peter

AU - Hindy, George

AU - Ericson, Ulrika

AU - Gullberg, Bo

AU - Bjartell, Anders

AU - Sonestedt, Emily

AU - Orho-Melander, Marju

AU - Wirfält, Elisabet

PY - 2014

Y1 - 2014

N2 - Variation in transcription factor 7-like 2 (TCF7L2), the strongest genetic risk factor for type 2 diabetes (T2D), may play a role in prostate cancer (PCa) depending on lifestyle factors. The aims of this study were to determine if TCF7L2 rs7903146 is associated with risk of PCa and if the association is modified by lifestyle factors independently of T2D status.

AB - Variation in transcription factor 7-like 2 (TCF7L2), the strongest genetic risk factor for type 2 diabetes (T2D), may play a role in prostate cancer (PCa) depending on lifestyle factors. The aims of this study were to determine if TCF7L2 rs7903146 is associated with risk of PCa and if the association is modified by lifestyle factors independently of T2D status.

UR - https://www.scopus.com/pages/publications/84904572975

U2 - 10.1002/pros.22832

DO - 10.1002/pros.22832

M3 - Article

C2 - 24961829

SN - 0270-4137

VL - 74

SP - 1161

EP - 1170

JO - The Prostate

JF - The Prostate

IS - 12

ER -

TCF7L2 type 2 diabetes risk variant, lifestyle factors, and incidence of prostate cancer.

Sammanfattning

FN:s Globala mål

Ämnesklassifikation (UKÄ)

Tillgång till dokument

Andra filer och länkar

Fingeravtryck

Forskningsoutput

Diabetes mellitus and risk of prostate cancer - A focus on shared risk factors and survivor bias

Citera det här