The DEK oncoprotein binds to highly and ubiquitously expressed genes with a dual role in their transcriptional regulation.

Carl Sandén; Linnea Järvstråt; Andreas Lennartsson; Per Ludvik Brattaas; Björn Nilsson; Urban Gullberg

doi:10.1186/1476-4598-13-215

The DEK oncoprotein binds to highly and ubiquitously expressed genes with a dual role in their transcriptional regulation.

Carl Sandén, Linnea Järvstråt, Andreas Lennartsson, Per Ludvik Brattaas, Björn Nilsson, Urban Gullberg

Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

228 Nedladdningar (Pure)

Sammanfattning

The DEK gene is highly expressed in a wide range of cancer cells, and a recurrent translocation partner in acute myeloid leukemia. While DEK has been identified as one of the most abundant proteins in human chromatin, its function and binding properties are not fully understood.

Originalspråk	engelska
Artikelnummer	215
Tidskrift	Molecular Cancer
Volym	13
DOI	https://doi.org/10.1186/1476-4598-13-215
Status	Published - 2014

Ämnesklassifikation (UKÄ)

Cancer och onkologi

FN:s Globala mål

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Tillgång till dokument

10.1186/1476-4598-13-215

BMC__Sanden_et_al

http://www.ncbi.nlm.nih.gov/pubmed/25216995?dopt=Abstract

1 Doktorsavhandling (sammanläggning)

Bioinformatic approaches to gene expression in leukemia. Networks and deconvolution
Bidragets översatta titel : BioinJärvstråt, L., 2017, Lund: Lund University: Faculty of Medicine. 42 s.
Forskningsoutput: Avhandling › Doktorsavhandling (sammanläggning)

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title = "The DEK oncoprotein binds to highly and ubiquitously expressed genes with a dual role in their transcriptional regulation.",

abstract = "The DEK gene is highly expressed in a wide range of cancer cells, and a recurrent translocation partner in acute myeloid leukemia. While DEK has been identified as one of the most abundant proteins in human chromatin, its function and binding properties are not fully understood.",

author = "Carl Sand{\'e}n and Linnea J{\"a}rvstr{\aa}t and Andreas Lennartsson and Brattaas, {Per Ludvik} and Bj{\"o}rn Nilsson and Urban Gullberg",

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AU - Sandén, Carl

AU - Järvstråt, Linnea

AU - Lennartsson, Andreas

AU - Brattaas, Per Ludvik

AU - Nilsson, Björn

AU - Gullberg, Urban

PY - 2014

Y1 - 2014

N2 - The DEK gene is highly expressed in a wide range of cancer cells, and a recurrent translocation partner in acute myeloid leukemia. While DEK has been identified as one of the most abundant proteins in human chromatin, its function and binding properties are not fully understood.

AB - The DEK gene is highly expressed in a wide range of cancer cells, and a recurrent translocation partner in acute myeloid leukemia. While DEK has been identified as one of the most abundant proteins in human chromatin, its function and binding properties are not fully understood.

U2 - 10.1186/1476-4598-13-215

DO - 10.1186/1476-4598-13-215

M3 - Article

C2 - 25216995

SN - 1476-4598

VL - 13

JO - Molecular Cancer

JF - Molecular Cancer

M1 - 215

ER -

The DEK oncoprotein binds to highly and ubiquitously expressed genes with a dual role in their transcriptional regulation.

Sammanfattning

Ämnesklassifikation (UKÄ)

FN:s Globala mål

Tillgång till dokument

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Forskningsoutput

Bioinformatic approaches to gene expression in leukemia. Networks and deconvolution

Citera det här