The granulation of a tablet formulation in a high-speed mixer, Diosna P25. Influence on intra-granular porosity and liquid saturation

N.-O. Lindberg; E. Hansson; Björn Holmquist

doi:10.3109/03639048709068371

The granulation of a tablet formulation in a high-speed mixer, Diosna P25. Influence on intra-granular porosity and liquid saturation

N.-O. Lindberg, E. Hansson, Björn Holmquist

Statistiska institutionen

Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

Sammanfattning

Intragranular porosity and liquid saturation were influenced by the impeller speed, the loss-on-drying of starch, the added amount of water and the drug concentration. A reduction of the impeller speed and the drug concentration decreased the porosity and increased the liquid saturation. Response surface contours were plotted.

Originalspråk	engelska
Sidor (från-till)	1069-1079
Tidskrift	Drug Development and Industrial Pharmacy
Volym	13
Nummer	6
DOI	https://doi.org/10.3109/03639048709068371
Status	Published - 1987

Ämnesklassifikation (UKÄ)

Sannolikhetsteori och statistik

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10.3109/03639048709068371

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title = "The granulation of a tablet formulation in a high-speed mixer, Diosna P25. Influence on intra-granular porosity and liquid saturation",

abstract = "Intragranular porosity and liquid saturation were influenced by the impeller speed, the loss-on-drying of starch, the added amount of water and the drug concentration. A reduction of the impeller speed and the drug concentration decreased the porosity and increased the liquid saturation. Response surface contours were plotted.",

author = "N.-O. Lindberg and E. Hansson and Bj{\"o}rn Holmquist",

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AB - Intragranular porosity and liquid saturation were influenced by the impeller speed, the loss-on-drying of starch, the added amount of water and the drug concentration. A reduction of the impeller speed and the drug concentration decreased the porosity and increased the liquid saturation. Response surface contours were plotted.

U2 - 10.3109/03639048709068371

DO - 10.3109/03639048709068371

M3 - Article

SN - 0363-9045

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EP - 1079

JO - Drug Development and Industrial Pharmacy

JF - Drug Development and Industrial Pharmacy

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The granulation of a tablet formulation in a high-speed mixer, Diosna P25. Influence on intra-granular porosity and liquid saturation

Sammanfattning

Ämnesklassifikation (UKÄ)

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