The mechanism of protein kinase C regulation

Forskningsoutput: TidskriftsbidragÖversiktsartikelPeer review

109 Nedladdningar (Pure)

Sammanfattning

Protein kinase C (PKC) is a family of serine/threonine protein kinases that plays a central role in transducing extracellular signals into a variety of intracellular responses ranging from cell proliferation to apoptosis. Nine PKC genes have been identified in the human genome, which encode 10 proteins. Each member of this protein kinase family displays distinct biochemical characteristics and is enriched in different cellular and subcellular locations. Activation of PKC has been implicated in the regulation of cell growth and differentiation. This review summarizes works of the past years in the field of PKC biochemistry that covers regulation and activation mechanism of different PKC isoforms.
Originalspråkengelska
Sidor (från-till)328-336
TidskriftFrontiers in Biology
Volym6
Nummer4
StatusPublished - 2011
Externt publiceradJa

Bibliografisk information

The information about affiliations in this record was updated in December 2015.
The record was previously connected to the following departments: Experimental Clinical Chemistry (013016010)

Ämnesklassifikation (UKÄ)

  • Läkemedelskemi

Fingeravtryck

Utforska forskningsämnen för ”The mechanism of protein kinase C regulation”. Tillsammans bildar de ett unikt fingeravtryck.

Citera det här