The Potential of MicroRNAs as Prostate Cancer Biomarkers.

Linda Fabris; Yvonne Ceder; Arul M Chinnaiyan; Guido W Jenster; Karina D Sorensen; Scott Tomlins; Tapio Visakorpi; George A Calin

doi:10.1016/j.eururo.2015.12.054

The Potential of MicroRNAs as Prostate Cancer Biomarkers.

Linda Fabris, Yvonne Ceder, Arul M Chinnaiyan, Guido W Jenster, Karina D Sorensen, Scott Tomlins, Tapio Visakorpi, George A Calin

Forskningsoutput: Tidskriftsbidrag › Översiktsartikel › Peer review

Sammanfattning

Short noncoding RNAs known as microRNAs (miRNAs) control protein expression through the degradation of RNA or the inhibition of protein translation. The miRNAs influence a wide range of biologic processes and are often deregulated in cancer. This family of small RNAs constitutes potentially valuable markers for the diagnosis, prognosis, and therapeutic choices in prostate cancer (PCa) patients, as well as potential drugs (miRNA mimics) or drug targets (anti-miRNAs) in PCa management.

Originalspråk	engelska
Sidor (från-till)	312-322
Tidskrift	European Urology
Volym	70
Nummer	2
Tidigt onlinedatum	2016 jan. 21
DOI	https://doi.org/10.1016/j.eururo.2015.12.054
Status	Published - 2016

Ämnesklassifikation (UKÄ)

Klinisk medicin

FN:s Globala mål

Denna forskningsoutput relaterar till följande Globala mål

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10.1016/j.eururo.2015.12.054

http://www.ncbi.nlm.nih.gov/pubmed/26806656?dopt=Abstract

Citera det här

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title = "The Potential of MicroRNAs as Prostate Cancer Biomarkers.",

abstract = "Short noncoding RNAs known as microRNAs (miRNAs) control protein expression through the degradation of RNA or the inhibition of protein translation. The miRNAs influence a wide range of biologic processes and are often deregulated in cancer. This family of small RNAs constitutes potentially valuable markers for the diagnosis, prognosis, and therapeutic choices in prostate cancer (PCa) patients, as well as potential drugs (miRNA mimics) or drug targets (anti-miRNAs) in PCa management.",

author = "Linda Fabris and Yvonne Ceder and Chinnaiyan, {Arul M} and Jenster, {Guido W} and Sorensen, {Karina D} and Scott Tomlins and Tapio Visakorpi and Calin, {George A}",

year = "2016",

doi = "10.1016/j.eururo.2015.12.054",

language = "English",

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pages = "312--322",

journal = "European Urology",

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T1 - The Potential of MicroRNAs as Prostate Cancer Biomarkers.

AU - Fabris, Linda

AU - Ceder, Yvonne

AU - Chinnaiyan, Arul M

AU - Jenster, Guido W

AU - Sorensen, Karina D

AU - Tomlins, Scott

AU - Visakorpi, Tapio

AU - Calin, George A

PY - 2016

Y1 - 2016

N2 - Short noncoding RNAs known as microRNAs (miRNAs) control protein expression through the degradation of RNA or the inhibition of protein translation. The miRNAs influence a wide range of biologic processes and are often deregulated in cancer. This family of small RNAs constitutes potentially valuable markers for the diagnosis, prognosis, and therapeutic choices in prostate cancer (PCa) patients, as well as potential drugs (miRNA mimics) or drug targets (anti-miRNAs) in PCa management.

AB - Short noncoding RNAs known as microRNAs (miRNAs) control protein expression through the degradation of RNA or the inhibition of protein translation. The miRNAs influence a wide range of biologic processes and are often deregulated in cancer. This family of small RNAs constitutes potentially valuable markers for the diagnosis, prognosis, and therapeutic choices in prostate cancer (PCa) patients, as well as potential drugs (miRNA mimics) or drug targets (anti-miRNAs) in PCa management.

U2 - 10.1016/j.eururo.2015.12.054

DO - 10.1016/j.eururo.2015.12.054

M3 - Review article

C2 - 26806656

SN - 1873-7560

VL - 70

SP - 312

EP - 322

JO - European Urology

JF - European Urology

IS - 2

ER -

The Potential of MicroRNAs as Prostate Cancer Biomarkers.

Sammanfattning

Ämnesklassifikation (UKÄ)

FN:s Globala mål

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