The Role of Mutation Bias in Adaptive Evolution

Erik I. Svensson, David Berger

Forskningsoutput: TidskriftsbidragÖversiktsartikelPeer review


Mutational input is the ultimate source of genetic variation, but mutations are not thought to affect the direction of adaptive evolution. Recently, critics of standard evolutionary theory have questioned the random and non-directional nature of mutations, claiming that the mutational process can be adaptive in its own right. We discuss here mutation bias in adaptive evolution. We find little support for mutation bias as an independent force in adaptive evolution, although it can interact with selection under conditions of small population size and when standing genetic variation is limited, entirely consistent with standard evolutionary theory. We further emphasize that natural selection can shape the phenotypic effects of mutations, giving the false impression that directed mutations are driving adaptive evolution.

Sidor (från-till)422-434
Antal sidor13
TidskriftTrends in Ecology and Evolution
Tidigt onlinedatum2019
StatusPublished - 2019

Ämnesklassifikation (UKÄ)

  • Evolutionsbiologi


Utforska forskningsämnen för ”The Role of Mutation Bias in Adaptive Evolution”. Tillsammans bildar de ett unikt fingeravtryck.

Citera det här