TY - JOUR
T1 - The Scandinavian Sarcoma Group Central Register
T2 - 6,000 patients after 25 years of monitoring of referral and treatment of extremity and trunk wall soft-tissue sarcoma
AU - Trovik, Clement
AU - Bauer, Henrik C F
AU - Styring, Emelie
AU - Sundby Hall, Kirsten
AU - Vult Von Steyern, Fredrik
AU - Eriksson, Sigvard
AU - Johansson, Ingela
AU - Sampo, Mika
AU - Laitinen, Minna
AU - Kalén, Anders
AU - Jónsson, Halldór
AU - Jebsen, Nina L
AU - Eriksson, Mikael
AU - Tukiainen, Erkki
AU - Wall, Najme
AU - Zaikova, Olga
AU - Sigurðsson, Helgi
AU - Lehtinen, Tuula
AU - Bjerkehagen, Bodil
AU - Skorpil, Mikael
AU - Egil Eide, Geir
AU - Johansson, Elisabeth
AU - Alvegard, Thor A.
PY - 2017/3/7
Y1 - 2017/3/7
N2 - Purpose — We wanted to examine the potential of the Scandinavian Sarcoma Group (SSG) Central Register, and evaluate referral and treatment practice for soft-tissue sarcomas in the extremities and trunk wall (STS) in the Nordic countries. Background — Based on incidence rates from the literature, 8,150 (7,000–9,300) cases of STS of the extremity and trunk wall should have been diagnosed in Norway, Finland, Iceland, and Sweden from 1987 through 2011. The SSG Register has 6,027 cases registered from this period, with 5,837 having complete registration of key variables. 10 centers have been reporting to the Register. The 5 centers that consistently report treat approximately 90% of the cases in their respective regions. The remaining centers have reported all the patients who were treated during certain time periods, but not for the entire 25-year period. Results — 59% of patients were referred to a sarcoma center untouched, i.e. before any attempt at open biopsy. There was an improvement from 52% during the first 5 years to 70% during the last 5 years. 50% had wide or better margins at surgery. Wide margins are now achieved less often than 20 years ago, in parallel with an increase in the use of radiotherapy. For the centers that consistently report, 97% of surviving patients are followed for more than 4 years. Metastasis-free survival (MFS) increased from 67% to 73% during the 25-year period. Interpretation — The Register is considered to be representative of extremity and trunk wall sarcoma disease in the population of Scandinavia, treated at the reporting centers. There were no clinically significant differences in treatment results at these centers.
AB - Purpose — We wanted to examine the potential of the Scandinavian Sarcoma Group (SSG) Central Register, and evaluate referral and treatment practice for soft-tissue sarcomas in the extremities and trunk wall (STS) in the Nordic countries. Background — Based on incidence rates from the literature, 8,150 (7,000–9,300) cases of STS of the extremity and trunk wall should have been diagnosed in Norway, Finland, Iceland, and Sweden from 1987 through 2011. The SSG Register has 6,027 cases registered from this period, with 5,837 having complete registration of key variables. 10 centers have been reporting to the Register. The 5 centers that consistently report treat approximately 90% of the cases in their respective regions. The remaining centers have reported all the patients who were treated during certain time periods, but not for the entire 25-year period. Results — 59% of patients were referred to a sarcoma center untouched, i.e. before any attempt at open biopsy. There was an improvement from 52% during the first 5 years to 70% during the last 5 years. 50% had wide or better margins at surgery. Wide margins are now achieved less often than 20 years ago, in parallel with an increase in the use of radiotherapy. For the centers that consistently report, 97% of surviving patients are followed for more than 4 years. Metastasis-free survival (MFS) increased from 67% to 73% during the 25-year period. Interpretation — The Register is considered to be representative of extremity and trunk wall sarcoma disease in the population of Scandinavia, treated at the reporting centers. There were no clinically significant differences in treatment results at these centers.
UR - http://www.scopus.com/inward/record.url?scp=85014579273&partnerID=8YFLogxK
U2 - 10.1080/17453674.2017.1293441
DO - 10.1080/17453674.2017.1293441
M3 - Article
C2 - 28266233
AN - SCOPUS:85014579273
SN - 1745-3674
VL - 88
SP - 341
EP - 347
JO - Acta Orthopaedica
JF - Acta Orthopaedica
IS - 3
ER -