Vitamin K and its Role in Diabetic Vascular Complications and Low-Grade Inflammation

Sofia Dahlberg, Ulf Schött

Forskningsoutput: TidskriftsbidragÖversiktsartikelPeer review

Sammanfattning

This review summarizes the involvement of vitamin K and the extrahepatic Gla proteins matrix Gla protein (MGP), Os-teocalcin (OC) and growth arrest-specific gene 6 protein (Gas6) in the development and progression of diabetes: in particular, complications related to angiopathy and inflammation. High vitamin K intake has been associated with a decreased risk of type 2 diabetes. Furthermore, in type 2 diabetic patients, the extent of artery calcification correlates to levels of the uncarboxylated Gla protein MGP, and supplementation with vitamin K has been shown to reduce oxidative stress markers as well as metabolic risk markers for diabetes.
Originalspråkengelska
ArtikelnummerJDBT-138
Antal sidor6
TidskriftJournal of Diabetes and Treatment
Volym2018
Utgåva1
DOI
StatusPublished - 2018 jan. 24

Ämnesklassifikation (UKÄ)

  • Endokrinologi och diabetes

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